17/04/19

High-throughput Discovery Lab Community Workshops

High-throughput Discovery Lab Community Workshop 2 - Leeds

As part of the Next Generation Chemistry for Medicine theme, Professor Adam Nelson, University of Leeds and NGC theme Leader, is leading the establishment of a high-throughput discovery lab that will be housed at the Rosalind Franklin Institute.

The purpose of the facility will be to facilitate the discovery of bioactive small molecules (not reaction discovery/optimisation for which other facilities are available).  It is envisaged that the lab be a national facility that will be used for three purposes:

  1. To enable the automation of new synthetic methods that would have value to drive future molecular discovery (by synthetic chemists);
  2. To facilitate the discovery of new chemical probes and drugs e.g. by progressing fragment hits identified at the high-throughput crystallography facility, XChem, at Diamond (by chemical biologists and medicinal chemists); and
  3. To realise entirely new workflows for molecular discovery.

Professor Nelson’s team are organising workshops to assist in specifying a laboratory that is fit for purpose.

We encourage a wide range of people to attend including both academics and postdoctoral researchers.

Please do circulate this email to people in your organisation who may be interested (e.g. academic colleagues, members of your group or network).

People who are interested in attending should provide the following information to Lucy Gray (l.v.gray@leeds.ac.uk) by 22nd March 2019:

  1. Name
  2. Email address
  3. Position/role
  4. Organisation
  5. Preferred workshop:  Oxford (8th April; 10.30-3) or Leeds (17th April; 10.30-3)
  6. Example of a reaction that could be automated at the facility (this could be a new reaction that is not currently exploited in discovery, or a reaction that is in the “standard” medicinal chemistry reaction toolkit).  We’d like delegates to present this at a workshop by completing this template.
  7. Specific dietary/access requirements

In the event that the workshops are over-subscribed, then we will select delegates to ensure that a diverse range of people/organisations/chemistry is represented.