Home Events Nanobody Discovery Workshop

The Rosalind Franklin Institute are delighted to invite you to our Nanobody Discovery Workshop, which will be taking place on 20th October.

Nanobodies are a versatile tools which have multiple applications in biomedical sciences due to their small molecular size, high affinity and high stability. They are extremely useful for stabilisation of structures in imaging work and, in recent years, there is growing interest in their use as therapeutics.

The Franklin wishes to bring together the UK community to discuss key areas around the development of high throughput nanobody technologies at this one day meeting.

Conference Organisers – Ray Owens and Caitlin Higgott

Nanobody structure

Agenda for the day:

9.30 Arrivals and registration (Coffee/tea available)


10:00 Introduction

Ray Owens (Nuffield Department of Medicine, University of Oxford & Rosalind Franklin Institute)


10:10 – 10.55 Keynote lecture:  Identification and Applications of Nanobodies

Serge Muyldermans (Structural Biology Research Centre, Vrije Universiteit Brussel


10.55 Coffee Break


11.15 -13.15 Invited short talks:

  • Nanobody selection from a large synthetic library using ribosome display

Huan Sun (Biomedical Sciences, University of Bristol)

  • Nanobodies as molecular tools for dissecting Solute Carrier function in the cell

Simon Newstead (Department of Biochemistry University of Oxford)

  • When Every Nanometer Counts – Nanobodies for Advanced Microscopy Applications

Laura Zanetti-Domingues (Central Laser Facility, Research Complex at Harwell)

  • Chemically modified nanobodies: novel tools and applications in imaging

Dimitrios Mamalis (Department of Chemistry University of Oxford & Chemistry, Rosalind Franklin Institute)

  • Towards a Nanobody Data Management and Analysis Pipeline with Antigen App

Alex Lubbock (AI and Informatics, Rosalind Franklin Institute)

  • Comparing antibody and nanobody binding sites

Eve Richardson (Department of Statistics, University of Oxford)


13:30 Lunch


14:15 – 14.45   Breakout sessions:

  • Generating nanobodies

(Rapporteur: Lauren Eyssen, Rosalind Franklin Institute)

  • Chemical modification and imaging

(Rapporteur: Siva Ramadurai, Rosalind Franklin Institute)

  • Bioinformatics and data management

(Rapporteur: Laura Shemilt, Rosalind Franklin Institute)


14:45 Refreshments


15:00 Feedback session


15:30 Close

Register for this workshop here through Eventbrite.

Rosalind Franklin Institute