Thesis title: Electron cryo-tomography of human induced pluripotent stem cell (iPSC)-derived neurons to study structural changes in Alzheimer’s disease
Primary theme: Structural Biology
Franklin supervisors: Dr Michael Grange, Professor Shabaz Mohammed and Dr Michele Darrow
University: University College London
University supervisors: Professor Selina Wray and Dr Charles Arber
Bronwen completed a BSc in Biology at the University of Sussex followed by an MSc in Neuroscience at King’s College London. Her PhD project uses iPSC-derived neurons to model Alzheimer’s disease specific structural changes in the endosomal lysosomal system through the use of electron cryo-tomography.