This new detector, named C100, is the key to making the cryo electron microscopy method more widely available. The project aims to reduce the amount of energy the detector requires from 200keV and 300keV (the current industry standards) to 100keV, with no loss of quality in resolution.

This reduction in energy enables the use of simpler, cheaper electron gun, and reduces the environmental requirements for the microscopes. This will allow greater access to this technology in a larger number of research laboratories and allow specialist labs to undertake more complex work- raising the standards of cryo-EM across the board.

This detector will then be incorporated into the CryoEM100 project, which is part of the ‘Electrifying Life Science’ grant funded by Wellcome.

Project team members at The Franklin:

Project partners: