Jake is a DPhil student on the Wellcome Trust Cellular Structural Biology programme at the University of Oxford. At undergraduate, he obtained an MChem (Hons) in Chemistry from the University of York, developing a keen interest in structural virology. Under the supervision of Professor Fred Antson, he undertook research projects characterising proteins in several human and bacterial viruses. Here at the Franklin, Jake’s work involves developing the methods to perform structural biology investigations in increasingly complex systems. In particular, he is focussed on understanding the mechanism that controls structural plasticity of the axon initial segment within brain tissue.