Cryo-EM
How Pathogens Interact with Human Cells
Our aim: To discover new ways of detecting, preventing and combatting human infectious diseases by discovering the mechanisms by which viruses and bacteria interact with human cells and tissues.
Multidimensional Imaging of Molecular Structures
Our aim: To develop new technologies to see the molecules of life and their dynamics with unprecedented detail.
New bifunctional, bispecific nanobodies scaffold helps with small protein imaging
Researchers at the Rosalind Franklin Institute, University of Oxford, and Diamond Light Source have combined their expertise to create new scaffolding molecules to allow the electron microscopy imaging of small proteins (below 50 kDa). Using this method the team have…
New scanning technique overcomes longstanding challenge in cryo-SEM imaging
Researchers at the Rosalind Franklin Institute have developed a new approach to scanning electron microscopy (SEM) that dramatically reduces obstructions caused by charging artefacts in frozen biological samples. The advance, described in a paper published in Nature Communications, allows scientists…