4D STEM

Project

Advanced Methods and Algorithms for Electron Ptychography of Biological Specimens

Electron ptychography is a powerful, dose-efficient imaging technique for studying biological specimens. This project will develop improved scanning and phase recovery methods to reduce the electron dose needed even further. This could enable high-resolution imaging of more delicate samples and reveal biological structures that are currently difficult to study.

Platform

Aberration-corrected transmission electron microscope

Ruska is an aberration-corrected transmission electron microscope (TEM) used to explore novel methods to study radiation sensitive specimens such as biological materials that have been cryogenically preserved or encapsulated in liquid for dynamic observations.

Technology Innovation Challenge

Multidimensional Imaging

Our aim: To develop new technologies to see the molecules of life in more detail including their dynamics and chemistry.