Cryo-EM

Technology Innovation Challenge

Multidimensional Imaging

Our aim: To develop new technologies to see the molecules of life in more detail including their dynamics and chemistry.

Science update

New bifunctional, bispecific nanobodies scaffold helps with small protein imaging

Researchers at the Rosalind Franklin Institute, University of Oxford, and Diamond Light Source have combined their expertise to create new scaffolding molecules to allow the electron microscopy imaging of small proteins (below 50 kDa). Using this method the team have…

Science update

New scanning technique overcomes longstanding challenge in cryo-SEM imaging

Researchers at the Rosalind Franklin Institute have developed a new approach to scanning electron microscopy (SEM) that dramatically reduces obstructions caused by charging artefacts in frozen biological samples. The advance, described in a paper published in Nature Communications, allows scientists…